A0A258EY34 · A0A258EY34_9RHOB

Function

function

Catalyzes the reversible oxidation of malate to oxaloacetate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

132050100150200250300
TypeIDPosition(s)Description
Binding site10-15NAD+ (UniProtKB | ChEBI)
Binding site34NAD+ (UniProtKB | ChEBI)
Binding site83substrate
Binding site89substrate
Binding site96NAD+ (UniProtKB | ChEBI)
Binding site119-121NAD+ (UniProtKB | ChEBI)
Binding site121substrate
Binding site152substrate
Active site176Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionL-lactate dehydrogenase activity
Molecular FunctionL-malate dehydrogenase (NAD+) activity
Biological Processlactate metabolic process
Biological Processpyruvate metabolic process
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Malate dehydrogenase
  • EC number

Gene names

    • Name
      mdh
    • ORF names
      B7Z10_07915

Organism names

Accessions

  • Primary accession
    A0A258EY34

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-143Lactate/malate dehydrogenase N-terminal
Domain148-303Lactate/malate dehydrogenase C-terminal

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 3 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    320
  • Mass (Da)
    33,317
  • Last updated
    2017-12-20 v1
  • Checksum
    98ECA1B5F70E9460
MARPKIALIGAGQIGGTLAHLLALKELGDVVLFDIAEGTPQGKALDLAQSGPVEGFDASLSGTNSYADLAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIKAHAPNAFVICITNPLDAMVWALREFSGLPHNKVVGMAGVLDSARFRHFLSVEFNVSMKDVTAFVLGGHGDTMVPSVRYSTVGGIPLPDLVAMGWTTQDKLDAIVQRTRDGGAEIVGLLKTGSAFYAPAASAVEMAEAYLKDQKRLLPCAAYVKGAYGLDGIYVGVPVIIGAAGVERVVEVKLDAAEQAMLDKSIDAVQGLLTACRAIDSSLP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NCDS01000095
EMBL· GenBank· DDBJ
OYX24907.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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