A0A250Y7D1 · A0A250Y7D1_CASCN
- ProteinAutism susceptibility gene 2 protein
- GeneAUTS2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1248 (go to sequence)
- Protein existencePredicted
- Annotation score1/5
Function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Glires (Rodents and rabbits) > Rodentia (rodent) > Castorimorpha (beavers and others) > Castoridae (beavers) > Castor
Accessions
- Primary accessionA0A250Y7D1
PTM/Processing
Keywords
- PTM
Structure
3D structure databases
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-89 | Disordered | ||||
Sequence: MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGVAGGGGAGRTRAPSLASSSGSDKEDNGKPPSSTPSRPRPPRRKRRESTSAEEDIID | ||||||
Compositional bias | 45-64 | Polar residues | ||||
Sequence: APSLASSSGSDKEDNGKPPS | ||||||
Region | 104-486 | Disordered | ||||
Sequence: KDVALKPQERVEKRQPPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKGLRQLKPGQSSCRDSDSDSASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDTSSEKLFNTVTVNKDSELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEQIFEPVVLKDPRLQVPQPVPQPQAEPQLQAPSPDPNLVQRTEAPPQPPPPNTQPPQGPPEVQLQPAPQPQVQRPPRPQSPTQLLHQTLPPVQAHPAQSLSQPLSVYNSSSLSLNSLSSSRSSTPAKSQPAPPHLSHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLPVPGHPAGST | ||||||
Compositional bias | 105-132 | Basic and acidic residues | ||||
Sequence: DVALKPQERVEKRQPPLTKKKREALTNG | ||||||
Compositional bias | 144-162 | Basic and acidic residues | ||||
Sequence: HPHHYSSDRENDRNLCQHL | ||||||
Compositional bias | 188-205 | Basic and acidic residues | ||||
Sequence: DSASGESKGFHRSSSRER | ||||||
Compositional bias | 206-221 | Polar residues | ||||
Sequence: LSDSSAPSSLGTGYFC | ||||||
Compositional bias | 276-293 | Basic and acidic residues | ||||
Sequence: RSQEKSQDCCKEQIFEPV | ||||||
Compositional bias | 302-316 | Pro residues | ||||
Sequence: VPQPVPQPQAEPQLQ | ||||||
Compositional bias | 325-363 | Pro residues | ||||
Sequence: VQRTEAPPQPPPPNTQPPQGPPEVQLQPAPQPQVQRPPR | ||||||
Compositional bias | 364-416 | Polar residues | ||||
Sequence: PQSPTQLLHQTLPPVQAHPAQSLSQPLSVYNSSSLSLNSLSSSRSSTPAKSQP | ||||||
Compositional bias | 429-451 | Polar residues | ||||
Sequence: PFPLSLPNHSPLHSFTPTLQPPA | ||||||
Compositional bias | 460-476 | Pro residues | ||||
Sequence: APPTALPPPPPLTSGSL | ||||||
Compositional bias | 770-791 | Polar residues | ||||
Sequence: PNSVFGHKDGPSVQNLSNPHEP | ||||||
Region | 770-1006 | Disordered | ||||
Sequence: PNSVFGHKDGPSVQNLSNPHEPWNRLHRTPPSFPTPPPWLKPGDLERSASAAAHDRDRDVDKRDSSVSKDDKERDSVEKRHSGHPSPAPVLPVGALGHARGSTEQIRGHLNPETREKDKPKEREREHSEPRKDLAAEEHKAKEGHLPDKDGPGDEAKQPAARPPSPYARPSSTSGGREAEVPRKGEAAFEHPKKGPEVKVKEERKEDHDLPPEAAPPGPRPTEPPANSSASAGPLAS | ||||||
Compositional bias | 817-851 | Basic and acidic residues | ||||
Sequence: SASAAAHDRDRDVDKRDSSVSKDDKERDSVEKRHS | ||||||
Compositional bias | 878-925 | Basic and acidic residues | ||||
Sequence: HLNPETREKDKPKEREREHSEPRKDLAAEEHKAKEGHLPDKDGPGDEA | ||||||
Compositional bias | 948-982 | Basic and acidic residues | ||||
Sequence: AEVPRKGEAAFEHPKKGPEVKVKEERKEDHDLPPE | ||||||
Region | 1106-1134 | Disordered | ||||
Sequence: PHDYSHHHHHHHHHGPLVAGDPRREHERG | ||||||
Region | 1200-1248 | Disordered | ||||
Sequence: TPPAAALSAPPPLISTLGGRPGSPRRTTPLSAEVRDRPPSHTLKDIEAR |
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,248
- Mass (Da)136,656
- Last updated2017-11-22 v1
- Checksum41EB39013665D5F6
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 45-64 | Polar residues | ||||
Sequence: APSLASSSGSDKEDNGKPPS | ||||||
Compositional bias | 105-132 | Basic and acidic residues | ||||
Sequence: DVALKPQERVEKRQPPLTKKKREALTNG | ||||||
Compositional bias | 144-162 | Basic and acidic residues | ||||
Sequence: HPHHYSSDRENDRNLCQHL | ||||||
Compositional bias | 188-205 | Basic and acidic residues | ||||
Sequence: DSASGESKGFHRSSSRER | ||||||
Compositional bias | 206-221 | Polar residues | ||||
Sequence: LSDSSAPSSLGTGYFC | ||||||
Compositional bias | 276-293 | Basic and acidic residues | ||||
Sequence: RSQEKSQDCCKEQIFEPV | ||||||
Compositional bias | 302-316 | Pro residues | ||||
Sequence: VPQPVPQPQAEPQLQ | ||||||
Compositional bias | 325-363 | Pro residues | ||||
Sequence: VQRTEAPPQPPPPNTQPPQGPPEVQLQPAPQPQVQRPPR | ||||||
Compositional bias | 364-416 | Polar residues | ||||
Sequence: PQSPTQLLHQTLPPVQAHPAQSLSQPLSVYNSSSLSLNSLSSSRSSTPAKSQP | ||||||
Compositional bias | 429-451 | Polar residues | ||||
Sequence: PFPLSLPNHSPLHSFTPTLQPPA | ||||||
Compositional bias | 460-476 | Pro residues | ||||
Sequence: APPTALPPPPPLTSGSL | ||||||
Compositional bias | 770-791 | Polar residues | ||||
Sequence: PNSVFGHKDGPSVQNLSNPHEP | ||||||
Compositional bias | 817-851 | Basic and acidic residues | ||||
Sequence: SASAAAHDRDRDVDKRDSSVSKDDKERDSVEKRHS | ||||||
Compositional bias | 878-925 | Basic and acidic residues | ||||
Sequence: HLNPETREKDKPKEREREHSEPRKDLAAEEHKAKEGHLPDKDGPGDEA | ||||||
Compositional bias | 948-982 | Basic and acidic residues | ||||
Sequence: AEVPRKGEAAFEHPKKGPEVKVKEERKEDHDLPPE |