A0A239K095 · A0A239K095_9MICO

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Note: Binds 1 thiamine pyrophosphate per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.

GO annotations

AspectTerm
Cellular Componentacetolactate synthase complex
Molecular Functionacetolactate synthase activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmagnesium ion binding
Molecular Functionthiamine pyrophosphate binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetolactate synthase
  • EC number

Gene names

    • ORF names
      SAMN06309944_2114

Organism names

Accessions

  • Primary accession
    A0A239K095

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-26Disordered
Domain26-142Thiamine pyrophosphate enzyme N-terminal TPP-binding
Domain216-351Thiamine pyrophosphate enzyme central
Domain415-570Thiamine pyrophosphate enzyme TPP-binding

Sequence similarities

Belongs to the TPP enzyme family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    605
  • Mass (Da)
    64,496
  • Last updated
    2017-11-22 v1
  • Checksum
    64A2A92FA63B3871
MSQKMTNPPGRPGPTTKTASTSSEVMTGAQSLVRSLEEVGVDTVFGIPGGAILPAYDPLMDSGKLRHILVRHEQAGGHAASGYAHATGRVGVTIATSGPGATNLVTPLADANMDSIPMVAITGQVGASLIGTDAFQEADIVGITLPVTKHNFLVTDPDEIPRVIAEAFHLAASGRPGPVLVDVAKSALQTDTKFQWPQEVQLPGYRPVTKPHGKQVREAAKLLATAKRPVLYVGGGIIRSGASDALRRLVDESGAAVVTTLMARGAVPDSHPQNLGMPGMHGTVAAVAALQKADLVVALGARFDDRVTGKLSSFAPKAAIVHADIDPAEIGKNRVVDVPIVGDLQEVITDLLPELAQEHEKNGKPDLGAWWRQIDDWRETYPLGYTPTADGLLAPQHVIERLGALSDPDAIFVAGVGQHQMWASQFIRYEHPNTWINSGGLGTMGYSVPAAMGAKVGQPDREVWAIDGDGCFQMTNQELATCVINEIPIKVAVINNSSLGMVRQWQTLFYDNRYSNTDLHTGHGTRRVPDFVKLAAAYGCAGLRAESEAEVDATIKRAKEIDDQPVIIDFTVSRDAMVWPMVAAGVSNDDIQYARGISPAWERED

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FZPE01000003
EMBL· GenBank· DDBJ
SNT10474.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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