A0A1X2J2A4 · A0A1X2J2A4_9FUNG
- ProteinDolichyl-phosphate-mannose--protein mannosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids760 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.
Catalytic activity
- a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H+
a di-trans,poly-cis-dolichyl β-D-mannosyl phosphate RHEA-COMP:19501 + RHEA-COMP:9863 = RHEA-COMP:13546 + a di-trans,poly-cis-dolichyl phosphate RHEA-COMP:19498 + CHEBI:15378
Pathway
Protein modification; protein glycosylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | dolichyl-phosphate-mannose-protein mannosyltransferase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDolichyl-phosphate-mannose--protein mannosyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Mucoromycotina > Mucoromycetes > Mucorales > Cunninghamellaceae > Absidia
Accessions
- Primary accessionA0A1X2J2A4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 44-66 | Helical | ||||
Sequence: LAHRVTFVGLTILSFFVSFYKIW | ||||||
Transmembrane | 133-152 | Helical | ||||
Sequence: VALRSLPATLNVLCVCLVYS | ||||||
Transmembrane | 184-204 | Helical | ||||
Sequence: IMLDSMLIFFMLATVYCYIRF | ||||||
Transmembrane | 216-233 | Helical | ||||
Sequence: WWIWLVATGVNMALTLSV | ||||||
Transmembrane | 239-259 | Helical | ||||
Sequence: FLVATIGIAVLVDLWALFDIR | ||||||
Transmembrane | 271-292 | Helical | ||||
Sequence: FYARAIALIIIPIAIYLFWFYV | ||||||
Transmembrane | 588-606 | Helical | ||||
Sequence: IGWYLGIGSVAVYAGILLA | ||||||
Transmembrane | 626-644 | Helical | ||||
Sequence: FLYNAGFFALLWLLHYGPF | ||||||
Transmembrane | 656-676 | Helical | ||||
Sequence: YLPAAVCNYMLLGAVLQFMLI | ||||||
Transmembrane | 713-735 | Helical | ||||
Sequence: FLAFGLILVCQIAMFLFLAPLTY |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-29 | Disordered | ||||
Sequence: MADTSLRNRRQPTDEKSLPAPPSPKQDNK | ||||||
Domain | 324-384 | MIR | ||||
Sequence: SLEIHYYDNITLLHRDTDVYLHSHDLEYPLRYDDGRISSKGQQVVGTKEFDVNSWWQVLPT | ||||||
Domain | 394-462 | MIR | ||||
Sequence: RVKVHHDDIIRLRHLETNTILLTHDVASPLLSTNEEITTVDPDTRYNETLFRLILEDSNNNDVWQTHLS |
Sequence similarities
Belongs to the glycosyltransferase 39 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length760
- Mass (Da)87,410
- Last updated2017-07-05 v1
- ChecksumA430E28686489CA6
Keywords
- Technical term