A0A1W9WJQ0 · A0A1W9WJQ0_9GAMM

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site12-19NADP+ (UniProtKB | ChEBI)
Binding site46NADP+ (UniProtKB | ChEBI)
Binding site88-89NADP+ (UniProtKB | ChEBI)
Binding site149NADP+ (UniProtKB | ChEBI)
Binding site179substrate
Binding site183substrate
Binding site217substrate
Binding site236substrate
Active site241Proton acceptor
Binding site341substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      B6247_24460

Organism names

Accessions

  • Primary accession
    A0A1W9WJQ0

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-188Glucose-6-phosphate dehydrogenase NAD-binding
Domain190-487Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    497
  • Mass (Da)
    58,139
  • Last updated
    2017-07-05 v1
  • Checksum
    F5DDD6FBC0B5D163
MIEEPCTYVIFGATGNLARIKLMPALYHLEVAGRLPESTMILATGRRPWNRDKWISEVREMLLAKARDGLDENVFKQFQERLHYFEGDLSDPNMYPKMREFINNDPVFPQNVAFYMSIRPAEFGVVVQNLSEGGLLNEEHGWRRVVIEKPFGYDLESARALHQQFSRHLREEQVYRIDHYLGKGTVQNVLVFRFANLMLEPLWNRNYIDHVQITHSETLGVGSRADYYDSAGAMRDMIQSHLLQLLTLVAMEPPVSMEAEALRDEKVKVLKSIRPIPPNAVHAQTFRAQYTTGFVQDQKVKGYLQEDKVPKHSVTETYAAMKLFIDNWRWAGVPFYLRTGKRLAEAQSMISICFKQPPQQFFRTSQIQRMRSNWILLGIQPTECIKAEMTVKEPGLEMNTRKISMDASFRKEDDIQKEAYEELLLDVIKGDRSLFLRYDEVEYAWRVVEPILRVWAMERDYIPTYPAGSWGPKESRRLFEKEDQRWRHSLLVEKEDS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NBMI01000216
EMBL· GenBank· DDBJ
OQY48921.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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