A0A1W6MTK4 · A0A1W6MTK4_9HYPH

  • Protein
    Palmitoyl-protein thioesterase ABHD10, mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate.

Catalytic activity

Keywords

  • Molecular function

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Palmitoyl-protein thioesterase ABHD10, mitochondrial
  • EC number
  • Alternative names
    • Acyl-protein thioesterase ABHD10
    • Alpha/beta hydrolase domain-containing protein 10
    • Mycophenolic acid acyl-glucuronide esterase, mitochondrial

Gene names

    • ORF names
      B1812_07480

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S285
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylocystaceae > Methylocystis

Accessions

  • Primary accession
    A0A1W6MTK4

Proteomes

Subcellular Location

Mitochondrion

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain54-268AB hydrolase-1

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    287
  • Mass (Da)
    31,046
  • Last updated
    2017-07-05 v1
  • Checksum
    4ADAD7D2DAFFCCAA
MTTEALLDFVTVPRDGAAAWRIARRRRPAPEGGKSRPGYVWLGGFASDMKGGKASFLDARAAASGRALLRFDYSGHGESAFDLPGGRFEDGSLGDWLEQSLALFLTSTQGPQLVIGSSMGSWIALRLAQRLEAIGEAKRLLGLVLIAPAVDFTEELILPTLSEAERRELDEGSGEIIRPAGRDGSPPLTRRLLEEGRRHLLLGGQMRSYAPVRILQGVRDEAVPWRHAFRVAEKLAADPVVVTLVAEGDHRLSRPEDLEQLAQTLERLEAEASSGAAYARASAISGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP019948
EMBL· GenBank· DDBJ
ARN80940.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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