A0A1V8UZR3 · A0A1V8UZR3_9PEZI
- ProteinNa(+)/H(+) antiporter
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids886 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | sodium:proton antiporter activity | |
Biological Process | intracellular potassium ion homeostasis | |
Biological Process | proton export across plasma membrane | |
Biological Process | regulation of membrane potential | |
Biological Process | sodium ion export across plasma membrane |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameNa(+)/H(+) antiporter
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Dothideomycetidae > Cladosporiales > Cladosporiaceae > Rachicladosporium
Accessions
- Primary accessionA0A1V8UZR3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 24-47 | Helical | ||||
Sequence: LHWFCYTILYECLFGAIYGVAVGY | ||||||
Transmembrane | 67-84 | Helical | ||||
Sequence: FLVFYFVLALFCAGSGSM | ||||||
Transmembrane | 118-138 | Helical | ||||
Sequence: VIDLLINLAFFVYFGTIIPWA | ||||||
Transmembrane | 144-163 | Helical | ||||
Sequence: YLGLDVWRLVVIAILVIFFR | ||||||
Transmembrane | 184-204 | Helical | ||||
Sequence: ALFAGHFGPIGVGAIFVAILA | ||||||
Transmembrane | 232-258 | Helical | ||||
Sequence: LIWPITTFLVITSIVVHGSSIAVFTLG |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-255 | Cation/H+ exchanger | ||||
Sequence: AFPFIYLAIYIIRYKGHPNEVALHWFCYTILYECLFGAIYGVAVGYIARRLIRWAHEKDIIDRESFLVFYFVLALFCAGSGSMLGMDDLLVGFAAGVGFSNDGWFTAQTEESHVSNVIDLLINLAFFVYFGTIIPWAQYNAGYLGLDVWRLVVIAILVIFFRRIPIMLALKPLIPDIKTWREALFAGHFGPIGVGAIFVAILARAELETEETTPLEVLPPPDFPHDNIIELIWPITTFLVITSIVVHGSSIAVF | ||||||
Region | 277-538 | Disordered | ||||
Sequence: GPSWMERLPRIQSRSKSSMSRYDSELDEKEKGPSPADLKPGTFLRRQAEEDNPSRAPSRNTSRHRSRKSKNFDNGRGPGGPISESAIRPSRREEASQPVSRSDSETLAAKSDSQPESPKGKSPEERGERDDDAQSPGEIFEQGEDTVFEDEDGKVLAVENESGVNPADREAGEVMEGKRLMREESAKDKDGDDGARDVDGPEETEAPQPKMSERPANNWRRGLNKAGTITKLAGLRNKEDKPKPEPRKTNGPARAYQYGNTI | ||||||
Domain | 280-831 | Alkali metal cation/H+ antiporter Nha1 C-terminal | ||||
Sequence: WMERLPRIQSRSKSSMSRYDSELDEKEKGPSPADLKPGTFLRRQAEEDNPSRAPSRNTSRHRSRKSKNFDNGRGPGGPISESAIRPSRREEASQPVSRSDSETLAAKSDSQPESPKGKSPEERGERDDDAQSPGEIFEQGEDTVFEDEDGKVLAVENESGVNPADREAGEVMEGKRLMREESAKDKDGDDGARDVDGPEETEAPQPKMSERPANNWRRGLNKAGTITKLAGLRNKEDKPKPEPRKTNGPARAYQYGNTIIVEDEDGEVIKKYDIPGADNGGGDSHRSRQRVARMGKMLGLGGADGNETPPSTTAAGEEGAAEPKQRPKPSRFGSLRPAAPEDEEDDEQLRFTISTGTRRMSKAEFIDQIRGMDPKARVQAVEASDAPEIVKKEARKDAREQAAAQKGRGKSVSGNVPVVHEQPDAESDAESPGGGGRRREAGNIERADSSDSADLKLVDSNNEQVPFHDLSSTVRNFRQPKPASSSANRSRATDDASPGSETAAQARRRAAAQASSSQSSSAAARDSNVETAAERRRREGALGISKEEDSSE | ||||||
Compositional bias | 296-311 | Basic and acidic residues | ||||
Sequence: SRYDSELDEKEKGPSP | ||||||
Compositional bias | 319-334 | Basic and acidic residues | ||||
Sequence: FLRRQAEEDNPSRAPS | ||||||
Compositional bias | 376-392 | Polar residues | ||||
Sequence: SRSDSETLAAKSDSQPE | ||||||
Compositional bias | 393-412 | Basic and acidic residues | ||||
Sequence: SPKGKSPEERGERDDDAQSP | ||||||
Compositional bias | 447-485 | Basic and acidic residues | ||||
Sequence: AGEVMEGKRLMREESAKDKDGDDGARDVDGPEETEAPQP | ||||||
Compositional bias | 510-524 | Basic and acidic residues | ||||
Sequence: GLRNKEDKPKPEPRK | ||||||
Region | 550-886 | Disordered | ||||
Sequence: KYDIPGADNGGGDSHRSRQRVARMGKMLGLGGADGNETPPSTTAAGEEGAAEPKQRPKPSRFGSLRPAAPEDEEDDEQLRFTISTGTRRMSKAEFIDQIRGMDPKARVQAVEASDAPEIVKKEARKDAREQAAAQKGRGKSVSGNVPVVHEQPDAESDAESPGGGGRRREAGNIERADSSDSADLKLVDSNNEQVPFHDLSSTVRNFRQPKPASSSANRSRATDDASPGSETAAQARRRAAAQASSSQSSSAAARDSNVETAAERRRREGALGISKEEDSSESEEESGEPRQVSPGQRGNIRFADGPSPPARAHVGAGGEGRGEGRGGIRWGSSVKG | ||||||
Compositional bias | 665-683 | Basic and acidic residues | ||||
Sequence: APEIVKKEARKDAREQAAA | ||||||
Compositional bias | 702-732 | Basic and acidic residues | ||||
Sequence: PDAESDAESPGGGGRRREAGNIERADSSDSA | ||||||
Compositional bias | 733-779 | Polar residues | ||||
Sequence: DLKLVDSNNEQVPFHDLSSTVRNFRQPKPASSSANRSRATDDASPGS | ||||||
Compositional bias | 788-806 | Polar residues | ||||
Sequence: RAAAQASSSQSSSAAARDS | ||||||
Compositional bias | 808-827 | Basic and acidic residues | ||||
Sequence: VETAAERRRREGALGISKEE |
Sequence similarities
Belongs to the fungal Na(+)/H(+) exchanger family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length886
- Mass (Da)96,713
- Last updated2017-06-07 v1
- ChecksumE79C551AEC396788
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 296-311 | Basic and acidic residues | ||||
Sequence: SRYDSELDEKEKGPSP | ||||||
Compositional bias | 319-334 | Basic and acidic residues | ||||
Sequence: FLRRQAEEDNPSRAPS | ||||||
Compositional bias | 376-392 | Polar residues | ||||
Sequence: SRSDSETLAAKSDSQPE | ||||||
Compositional bias | 393-412 | Basic and acidic residues | ||||
Sequence: SPKGKSPEERGERDDDAQSP | ||||||
Compositional bias | 447-485 | Basic and acidic residues | ||||
Sequence: AGEVMEGKRLMREESAKDKDGDDGARDVDGPEETEAPQP | ||||||
Compositional bias | 510-524 | Basic and acidic residues | ||||
Sequence: GLRNKEDKPKPEPRK | ||||||
Compositional bias | 665-683 | Basic and acidic residues | ||||
Sequence: APEIVKKEARKDAREQAAA | ||||||
Compositional bias | 702-732 | Basic and acidic residues | ||||
Sequence: PDAESDAESPGGGGRRREAGNIERADSSDSA | ||||||
Compositional bias | 733-779 | Polar residues | ||||
Sequence: DLKLVDSNNEQVPFHDLSSTVRNFRQPKPASSSANRSRATDDASPGS | ||||||
Compositional bias | 788-806 | Polar residues | ||||
Sequence: RAAAQASSSQSSSAAARDS | ||||||
Compositional bias | 808-827 | Basic and acidic residues | ||||
Sequence: VETAAERRRREGALGISKEE |
Keywords
- Technical term