A0A1U7QNL2 · A0A1U7QNL2_MESAU

Function

Features

Showing features for dna binding.

134950100150200250300
TypeIDPosition(s)Description
DNA binding181-240Homeobox

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromatin
Cellular Componentnucleus
Molecular FunctionbHLH transcription factor binding
Molecular FunctionDNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Functionmetal ion binding
Molecular Functionpromoter-specific chromatin binding
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular FunctionRNA polymerase II-specific DNA-binding transcription factor binding
Biological Processatrial septum morphogenesis
Biological Processcanonical Wnt signaling pathway
Biological Processcardiac cell fate determination
Biological Processcardiac muscle cell myoblast differentiation
Biological Processcardiac right ventricle morphogenesis
Biological Processcell population proliferation
Biological Processendocardial cushion morphogenesis
Biological Processinnervation
Biological Processnegative regulation of canonical Wnt signaling pathway
Biological Processnegative regulation of inflammatory response
Biological Processnegative regulation of neuron apoptotic process
Biological Processnegative regulation of neuron differentiation
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processneural crest cell migration
Biological Processoutflow tract septum morphogenesis
Biological Processpancreas development
Biological Processperipheral nervous system neuron axonogenesis
Biological Processpharyngeal system development
Biological Processpituitary gland development
Biological Processpositive regulation of angiogenesis
Biological Processpositive regulation of cell differentiation
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of granulocyte colony-stimulating factor production
Biological Processpositive regulation of granulocyte macrophage colony-stimulating factor production
Biological Processpositive regulation of insulin secretion
Biological Processpositive regulation of interleukin-1 alpha production
Biological Processpositive regulation of interleukin-1 beta production
Biological Processpositive regulation of interleukin-12 production
Biological Processpositive regulation of interleukin-6 production
Biological Processpositive regulation of tumor necrosis factor production
Biological Processpositive regulation of type II interferon production
Biological Processpositive regulation of tyrosine phosphorylation of STAT protein
Biological Processpositive regulation of vascular endothelial growth factor production
Biological Processregulation of heart rate by cardiac conduction
Biological Processregulation of secondary heart field cardioblast proliferation
Biological Processretinal ganglion cell axon guidance
Biological Processsecondary heart field specification
Biological Processsensory system development
Biological Processsinoatrial node cell development
Biological Processspinal cord motor neuron cell fate specification
Biological Processtranscription by RNA polymerase II
Biological Processtrigeminal nerve development
Biological Processventricular cardiac muscle tissue morphogenesis
Biological Processvisceral motor neuron differentiation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Insulin gene enhancer protein ISL-1

Gene names

    • Name
      Isl1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Cricetidae > Cricetinae > Mesocricetus

Accessions

  • Primary accession
    A0A1U7QNL2

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain15-77LIM zinc-binding
Domain78-139LIM zinc-binding
Domain179-239Homeobox
Compositional bias312-341Polar residues
Region312-349Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    349
  • Mass (Da)
    39,036
  • Last updated
    2017-05-10 v1
  • Checksum
    4DB82FD09154F404
MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias312-341Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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