A0A1T4PYW4 · A0A1T4PYW4_9FIRM
- ProteindTTP/UTP pyrophosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids215 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- H2O + UTP = diphosphate + H+ + UMP
Cofactor
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 13 | Important for substrate specificity | ||||
Sequence: R | ||||||
Active site | 97 | Proton acceptor | ||||
Sequence: D | ||||||
Site | 98 | Important for substrate specificity | ||||
Sequence: T | ||||||
Site | 180 | Important for substrate specificity | ||||
Sequence: Q |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | dTTP diphosphatase activity | |
Molecular Function | UTP diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedTTP/UTP pyrophosphatase
- EC number
- Short namesdTTPase/UTPase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Eubacteriaceae > Eubacterium
Accessions
- Primary accessionA0A1T4PYW4
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length215
- Mass (Da)24,158
- Last updated2017-05-10 v1
- ChecksumC4BE251CE946FFD2
Keywords
- Technical term