A0A1T4PYW4 · A0A1T4PYW4_9FIRM

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site13Important for substrate specificity
Active site97Proton acceptor
Site98Important for substrate specificity
Site180Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      SAMN02745110_02182

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ATCC 17233
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Eubacteriaceae > Eubacterium

Accessions

  • Primary accession
    A0A1T4PYW4

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    215
  • Mass (Da)
    24,158
  • Last updated
    2017-05-10 v1
  • Checksum
    C4BE251CE946FFD2
MSLRVILASQSPRRQELLKKIFQYFEVMPSNADENIEVLPPAEYVEKLSKIKALEVYERLMDEDEMVPEVTGMKRLSKLFKGSGYASTEDMLVIGADTIVVRDGEILGKPKDEEDAFAILKTLQGRGHEVYTGVTLIHNEETISFSVKTDVHIVPMSDEEINEYIKTKDPMDKAGAYGIQTVFTKFVSGIEGDYNNVVGLPVSAIYSRLKDMKIV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FUXA01000015
EMBL· GenBank· DDBJ
SJZ96497.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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