A0A1T1J362 · A0A1T1J362_9GAMM
- ProteinPeptide methionine sulfoxide reductase MsrA
- GenemsrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids179 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Catalytic activity
- [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:57844 + CHEBI:15377 = CHEBI:58772 + RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 11 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | L-methionine:thioredoxin-disulfide S-oxidoreductase activity | |
Molecular Function | peptide-methionine (S)-S-oxide reductase activity | |
Biological Process | protein modification process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptide methionine sulfoxide reductase MsrA
- EC number
- Short namesProtein-methionine-S-oxide reductase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter
Accessions
- Primary accessionA0A1T1J362
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-151 | Peptide methionine sulphoxide reductase MsrA | ||||
Sequence: AVLAGGCFWGMQDLIRKRPGIISTRVGYTGGDIPNATYRNHGTHAEGIEIVFDPTVTSYRNILEFFFQIHDPTTLNRQGNDRGLSYRSGIYYVDEEQKRVAEDTIADVDASGLWDGKVVTEVQPVGEFWEAEPDHQDYLEKRPGGYT |
Sequence similarities
Belongs to the MsrA Met sulfoxide reductase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length179
- Mass (Da)20,154
- Last updated2017-05-10 v1
- Checksum01E427DB371F7CFF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MVOM01000069 EMBL· GenBank· DDBJ | OOW08877.1 EMBL· GenBank· DDBJ | Genomic DNA |