A0A1Q8YD47 · A0A1Q8YD47_9BURK
- ProteinPhospho-2-dehydro-3-deoxyheptonate aldolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids380 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
Catalytic activity
- D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-deoxy-7-phosphoheptulonate synthase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhospho-2-dehydro-3-deoxyheptonate aldolase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Rhodoferax
Accessions
- Primary accessionA0A1Q8YD47
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-31 | Disordered | ||||
Sequence: MNAKTVVSADPDAWNHSLNANAPDRTGQTDN | ||||||
Compositional bias | 12-27 | Polar residues | ||||
Sequence: DAWNHSLNANAPDRTG | ||||||
Domain | 67-366 | DAHP synthetase I/KDSA | ||||
Sequence: NIHNITTGKDDRVLVVIGPCSIHDPAAAMEYARKLKVQREKYADSLEIVMRVYFEKPRTTVGWKGLINDPYLDESFRIDEGLRMARQLLIDINRLGLPAGSEFLDVISPQYLGDLISWGAIGARTTESQVHRELASGLSAPIGFKNGTDGNIRIATDAIHAAAGGHHFLSVHKNGQVAIVQTKGNKDCHVILRGGKAPNFDAVSVAAACTELEKSKLPQTLMVDCSHANSSKQHEKQIDVARDIAGQISGGSKQVFGVMVESHLSAGAQKFTPGKDKTDKLVYGQSITDACLGWDDSLQV |
Sequence similarities
Belongs to the class-I DAHP synthase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length380
- Mass (Da)41,328
- Last updated2017-04-12 v1
- Checksum7EC7818280281491
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 12-27 | Polar residues | ||||
Sequence: DAWNHSLNANAPDRTG |
Keywords
- Technical term