A0A1Q8Q3A0 · A0A1Q8Q3A0_9BACI

  • Protein
    Glucose-6-phosphate 1-dehydrogenase
  • Gene
    zwf
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site7-14NADP+ (UniProtKB | ChEBI)
Binding site41NADP+ (UniProtKB | ChEBI)
Binding site84-85NADP+ (UniProtKB | ChEBI)
Binding site147NADP+ (UniProtKB | ChEBI)
Binding site177substrate
Binding site181substrate
Binding site215substrate
Binding site234substrate
Active site239Proton acceptor
Binding site338substrate
Binding site343substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      BTO30_12965

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • XD80
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Domibacillus

Accessions

  • Primary accession
    A0A1Q8Q3A0

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-186Glucose-6-phosphate dehydrogenase NAD-binding
Domain192-472Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    478
  • Mass (Da)
    54,610
  • Last updated
    2017-04-12 v1
  • Checksum
    7CE198147C1993D0
MTFVLFGATGDLAKRKIFPALYNLFMDGKMPDSFSIVGVGRREWSDQTFQSHVEESVHTFSRRIINDASNMKTFLQAFRYSPLDVTKSDEYQSLLETVQQQEKNLSIPENRLFYLSVSPEFVDAITSNIKQSGLGTVKGWKRLIVEKPFGHDLTSARELNEKLSRTFEEEEMYRIDHYLGKPMVQNLESLVYTNPLLRAIWNKDHIVNVQITASEVVGVEERAGYYDRAGAIRDMVQNHMLQMVMMTAMQISKKGAEEVNDEKRKVMESLRPLQKEDVAANVIRGQYGPGEIKGEPVTAYENEPGVSPSSKNDTFIAARLWIDNDFWAGVPFYIRTGKRMQEKSTRIVVEFKNPLSAETAPNRLTIDISPSEGVSLQLNMKNPLNNQIEPVSIDFSANAKDVPEAYELLLFGALRGDPTFFAHWKEVELSWEWVQPILDAFEEDLVPLHLYRSGSMGPEASYQLLQEDGFKWLDHEQK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MSDU01000031
EMBL· GenBank· DDBJ
OLN21807.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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