A0A1Q7TBE9 · A0A1Q7TBE9_9BACT

Function

function

Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s2U34.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site, active site, site.

134250100150200250300
TypeIDPosition(s)Description
Binding site26ATP (UniProtKB | ChEBI)
Active site94Nucleophile
Binding site118ATP (UniProtKB | ChEBI)
Site119Interaction with tRNA
Site317Interaction with tRNA

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctiontRNA binding
Molecular FunctiontRNA-uridine 2-sulfurtransferase activity
Biological ProcesstRNA wobble position uridine thiolation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-specific 2-thiouridylase MnmA
  • EC number

Gene names

    • Name
      mnmA
    • ORF names
      AUG81_12160

Organism names

Accessions

  • Primary accession
    A0A1Q7TBE9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region148-150Interaction with tRNA
Domain186-240tRNA-specific 2-thiouridylase MnmA-like central
Domain248-333tRNA-specific 2-thiouridylase MnmA-like C-terminal
Region284-285Interaction with tRNA

Sequence similarities

Belongs to the MnmA/TRMU family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    342
  • Mass (Da)
    37,754
  • Last updated
    2017-04-12 v1
  • Checksum
    6219A78B4CA09053
MSGGVDSSVAGYLLREQGYDVIGVTMKVWPQDCISRAEDKCCGPQAVADARGVARALGIPHYVVDEADQFEKLVISYFSSEYQAGRTPNPCVMCNEKLKFGNLWEKAKGLGCDYIATGHYAIIEHRHATNGDRDYTRAVLRKGIDSRKDQSYFLFSLRQEQLQRALTPLGRMSKSEIRAHLGQNQFHPGGIYDLDGNFIAGHDGIEMFTIGQRKGLPGGSAQPRYVVDLDPETNRVIVGQAEDLLVEEFEIDRVNWISGAGNDDPGPRSATAATMAHEVTVKIRYNHPGTRATLMPMENQRARIRLHDPQKAVTPGQAAVFYDDDLVLGGGWICRQAELVAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MNIL01000147
EMBL· GenBank· DDBJ
OLD85820.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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