A0A1I6ZYX4 · A0A1I6ZYX4_9GAMM

  • Protein
    Pyridoxine/pyridoxamine 5'-phosphate oxidase
  • Gene
    pdxH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Note: Binds 1 FMN per subunit.

Pathway

Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site9-12substrate
Binding site62-67FMN (UniProtKB | ChEBI)
Binding site67substrate
Binding site77-78FMN (UniProtKB | ChEBI)
Binding site84FMN (UniProtKB | ChEBI)
Binding site106FMN (UniProtKB | ChEBI)
Binding site124substrate
Binding site128substrate
Binding site132substrate
Binding site141-142FMN (UniProtKB | ChEBI)
Binding site186FMN (UniProtKB | ChEBI)
Binding site192-194substrate
Binding site196FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionFMN binding
Molecular Functionpyridoxamine phosphate oxidase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine/pyridoxamine 5'-phosphate oxidase
  • EC number
  • Alternative names
    • PNP/PMP oxidase
      (PNPOx
      )
    • Pyridoxal 5'-phosphate synthase

Gene names

    • Name
      pdxH
    • ORF names
      SAMN04487956_11430

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CGMCC 1.6493
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Oceanospirillales > Halomonadaceae > Halomonas

Accessions

  • Primary accession
    A0A1I6ZYX4

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-120Pyridoxamine 5'-phosphate oxidase putative
Domain173-213Pyridoxine 5'-phosphate oxidase dimerisation C-terminal

Sequence similarities

Belongs to the pyridoxamine 5'-phosphate oxidase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    213
  • Mass (Da)
    24,546
  • Last updated
    2017-11-22 v1
  • Checksum
    3A5F2CAC56A454C3
MTRNIADIRRDYEGGQLDEADSPDEPMTLFDEWLTLALDTEGSDGNAMTLATADSQGRPHARIVLLKGTDEKGMVFFTNYHSHKGSELANVPHASLVFWWPGLSRQVRVEGRVEQVSPEESDTYFASRPRGSQLGAWVATQSVVIPDRSWLAQREQRFEHAYEGQEIPRPIHWGGYRVIPDMIEFWQGQPSRLHDRLRYERRDGSWHRFRLAP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FPAQ01000014
EMBL· GenBank· DDBJ
SFT67865.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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