A0A1I2B4F3 · A0A1I2B4F3_9GAMM

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site64substrate
Binding site140substrate
Binding site165substrate
Binding site166-168NAD+ (UniProtKB | ChEBI)
Binding site195substrate
Binding site199substrate
Binding site200NAD+ (UniProtKB | ChEBI)
Binding site229-234NAD+ (UniProtKB | ChEBI)
Binding site231-236NAD+ (UniProtKB | ChEBI)
Binding site252NAD+ (UniProtKB | ChEBI)
Binding site301NAD+ (UniProtKB | ChEBI)
Binding site322-324NAD+ (UniProtKB | ChEBI)
Binding site370NAD+ (UniProtKB | ChEBI)
Binding site377NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      SAMN04487869_10949

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 26671
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Marinobacteraceae > Marinobacter

Accessions

  • Primary accession
    A0A1I2B4F3

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain200-376S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    464
  • Mass (Da)
    51,172
  • Last updated
    2017-11-22 v1
  • Checksum
    1CA6ABA513EF8EA2
MSTPAEKLNSFDDYKVRNISLAGWGRKEINIAEGEMPALMKLREKYKAEQPLKGANVMGCIHMTIQTAVLIETLIELGANVRWSSCNIFSTQDQAAAAIAAQGIPVFAWKGETDEEYDWCLERTVGADVDGWEPNMILDDGGDLTALLHEKYPEILANCHGVTEETTTGVHRLQEMLREGTLKVPAINVNDAVTKAKNDNKYGCRHSLNDAIKRATDHLMAGKKALVIGYGDVGKGSAASLRQEGMIVKVTEADPICAMQACMDGFEVVSPYIDGVNTGTESAVNRDLLQNTDLLVTTTGNMNVCDAHMLKALKSGAVVCNIGHFDNEIDTAYMRKNWEWDEVKPQVHVVYRDKATNDHLILLSEGRLVNLGNATGHPSRIMDGSFANQVLAQMYLFERKFADLPEDAREKGVYVQVLPKHLDEEVARAMVEGFGGVITKMTPEQAKYIGVPVEGPYKPESYKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FONF01000009
EMBL· GenBank· DDBJ
SFE50867.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp