A0A1H9ADD2 · A0A1H9ADD2_9FLAO

  • Protein
    Allosteric NADP-dependent malic enzyme
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site.

1764100200300400500600700
TypeIDPosition(s)Description
Binding site77-84NADP+ (UniProtKB | ChEBI)
Active site95Proton acceptor
Binding site137a divalent metal cation (UniProtKB | ChEBI)
Binding site138a divalent metal cation (UniProtKB | ChEBI)
Binding site163a divalent metal cation (UniProtKB | ChEBI)
Binding site287a divalent metal cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionacyltransferase activity
Molecular Functionmalic enzyme activity
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processmalate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Allosteric NADP-dependent malic enzyme

Gene names

    • ORF names
      SAMN05421824_0209

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 21035
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae

Accessions

  • Primary accession
    A0A1H9ADD2

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-152Malic enzyme N-terminal
Domain164-400Malic enzyme NAD-binding

Sequence similarities

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
In the N-terminal section; belongs to the malic enzymes family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    764
  • Mass (Da)
    84,870
  • Last updated
    2017-11-22 v1
  • Checksum
    583AE9E7FF6B4481
MSEESKRREALIYHAKPTPGKIKVVPTKKYASQRDLSLAYSPGVAEPCLEIEKDKNNAYRYTAKGNLVAVISNGTAVLGLGNIGPEASKPVMEGKGLLFKIFADIDVFDIEVDTEDVDAFIETVKNIAPTFGGINLEDIKAPEAFEIERRLKEELDIPVMHDDQHGTAIISAAALINALELAKKNIEDVKIVISGAGAAAISCSRLYQSCGAKRENMVMLDSKGVIRDDRDNLTSQKAEFATHRKIDTLEEAMIDADVFIGLSMADIVTPEMLKTMAKDPIVFAMANPNPEIKYQLAVDTRDDIIMATGRSDHPNQVNNVLGFPFIFRGALDVRASKINEEMKIAAVKALAALAKEPVPEQVNVAYEQTRLAFGRKYIIPKPFDPRLIAEIPPAVAKAAMESGVAKESITDWEKYKNSLRERLGSDNKLVRLLLSRAKLNPKRVVYAEADQLAVLKAAQIAHEEGIAIPILLGRKETIETLMKEIDFEADISIIDPKTEEENERKNRYAKVYWEQRKRRGVTYYAAQRLMRERNYFAAMMVNEGDADALISGYSRNYPSVVKPMLELIGMAKGATRIATTNVMMTKRGPMFLSDTSINIDPSAKDLAKIAVMTSKVIKTFGFEPVIAMTSYSNFGSSDNERASKVREAVSMLHRHYPELVVDGELQTDFALNDQMLRDQFPFSKLVGRKVNSLIFPNLDAANITYKLLKELNEADSIGPIMMGMKKPVHILQLDASVDEIVNMTAVAVIDAQNKEMWELEKDIS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FOFN01000001
EMBL· GenBank· DDBJ
SEP74443.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp