A0A1H9ADD2 · A0A1H9ADD2_9FLAO
- ProteinAllosteric NADP-dependent malic enzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids764 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 77-84 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: VLGLGNIG | ||||||
Active site | 95 | Proton acceptor | ||||
Sequence: K | ||||||
Binding site | 137 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 138 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 163 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 287 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | acyltransferase activity | |
Molecular Function | malic enzyme activity | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | |
Biological Process | malate metabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae
Accessions
- Primary accessionA0A1H9ADD2
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 19-152 | Malic enzyme N-terminal | ||||
Sequence: PGKIKVVPTKKYASQRDLSLAYSPGVAEPCLEIEKDKNNAYRYTAKGNLVAVISNGTAVLGLGNIGPEASKPVMEGKGLLFKIFADIDVFDIEVDTEDVDAFIETVKNIAPTFGGINLEDIKAPEAFEIERRLK | ||||||
Domain | 164-400 | Malic enzyme NAD-binding | ||||
Sequence: QHGTAIISAAALINALELAKKNIEDVKIVISGAGAAAISCSRLYQSCGAKRENMVMLDSKGVIRDDRDNLTSQKAEFATHRKIDTLEEAMIDADVFIGLSMADIVTPEMLKTMAKDPIVFAMANPNPEIKYQLAVDTRDDIIMATGRSDHPNQVNNVLGFPFIFRGALDVRASKINEEMKIAAVKALAALAKEPVPEQVNVAYEQTRLAFGRKYIIPKPFDPRLIAEIPPAVAKAAM |
Sequence similarities
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
In the N-terminal section; belongs to the malic enzymes family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length764
- Mass (Da)84,870
- Last updated2017-11-22 v1
- Checksum583AE9E7FF6B4481
Keywords
- Technical term