A0A1H7H7E3 · A0A1H7H7E3_9SPHN
- ProteinShikimate kinase
- GenearoK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids179 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Catalytic activity
- shikimate + ATP = 3-phosphoshikimate + ADP + H+
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 23-28 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GVGKST | ||||||
Binding site | 27 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 45 | substrate | ||||
Sequence: D | ||||||
Binding site | 69 | substrate | ||||
Sequence: R | ||||||
Binding site | 91 | substrate | ||||
Sequence: G | ||||||
Binding site | 129 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 148 | substrate | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | shikimate kinase activity | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameShikimate kinase
- EC number
- Short namesSK
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas
Accessions
- Primary accessionA0A1H7H7E3
Proteomes
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length179
- Mass (Da)19,591
- Last updated2017-11-22 v1
- Checksum9377BFEFBD5F16F9
Keywords
- Technical term