A0A1H5VXJ1 · A0A1H5VXJ1_9ACTN

  • Protein
    Release factor glutamine methyltransferase
  • Gene
    prmC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

Catalytic activity

Features

Showing features for binding site.

128620406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site119-123S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site142S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site171S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site188S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site188-191substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionnucleic acid binding
Molecular Functionprotein-(glutamine-N5) methyltransferase activity
Molecular Functionprotein-glutamine N-methyltransferase activity
Biological Processmethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Release factor glutamine methyltransferase
  • EC number
  • Short names
    RF MTase
  • Alternative names
    • N5-glutamine methyltransferase PrmC
    • Protein-(glutamine-N5) MTase PrmC
    • Protein-glutamine N-methyltransferase PrmC

Gene names

    • Name
      prmC
    • ORF names
      SAMN04489712_102507

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 43163
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Streptosporangiales > Thermomonosporaceae > Thermomonospora

Accessions

  • Primary accession
    A0A1H5VXJ1

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-72Release factor glutamine methyltransferase N-terminal
Domain111-191Methyltransferase small

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    31,563
  • Last updated
    2017-01-18 v1
  • Checksum
    EACC97EEAE045F2D
MNLLLDEVARATARLADAGVASPRADAEELAAAVHGVKRSELHTVPDSAFDARFWEGVARREAGEPLQHITGRAFFRFLELKVGPGVFVPRPETEVMVGWALDTLRDMDVQDPLVVDLGTGSGAIALSIAQEAPRARVHAVEKDPKAFVHATRNVEALDERGRVRLHLADFADALGELDGTVDLVVSNPPYIPMSEWEYVPPDVRDHDPAAALWGGGDDGLDAIRVVERTARRLLRPGGHVAVEHSDLQGNAVYWVFAEEHGWRDVRNRRDLTDRDRFVTARLSRD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FNVO01000002
EMBL· GenBank· DDBJ
SEF91995.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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