A0A1H5SQN7 · A0A1H5SQN7_9CLOT

  • Protein
    D-alanine--D-alanine ligase
  • Gene
    ddl
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cell wall formation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site16
Binding site145ATP (UniProtKB | ChEBI)
Binding site190-192ATP (UniProtKB | ChEBI)
Active site198
Binding site198-199ATP (UniProtKB | ChEBI)
Binding site228-236ATP (UniProtKB | ChEBI)
Binding site317Mg2+ 1 (UniProtKB | ChEBI)
Binding site330-331ATP (UniProtKB | ChEBI)
Binding site331Mg2+ 1 (UniProtKB | ChEBI)
Binding site331Mg2+ 2 (UniProtKB | ChEBI)
Binding site333Mg2+ 2 (UniProtKB | ChEBI)
Active site340

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionD-alanine-D-alanine ligase activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-alanine--D-alanine ligase
  • EC number
  • Alternative names
    • D-Ala-D-Ala ligase
    • D-alanylalanine synthetase

Gene names

    • Name
      ddl
    • ORF names
      SAMN05660865_00434

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 5463
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Clostridiaceae > Caloramator

Accessions

  • Primary accession
    A0A1H5SQN7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain149-360ATP-grasp

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    393
  • Mass (Da)
    44,628
  • Last updated
    2017-01-18 v1
  • Checksum
    7BDC940301E4A9CB
MEKKNVLVMFGGRSVEHEVSVITGLQVVENIDKEKYNVIPLFITKQGEWYTGDVLLDIKNYRDLNELLKKANRVYIEPIPNNPYLKFYPEKGLFKRTKDPIRIDVVFPALHGTHGEDGTIQGLLELCNIPYVGSGVLGSAVGMDKIIMKDIFKANGIPIVNYTWFLRKDYINDSEKVLKHIEEKLKYPMFVKPANLGSSIGISKAKNREELINAIEIAINYDRKVIVEEAVNNPMEINCSVIGFDNDYQASVLEQPVSWQEFLSFEDKYLRGNKNSGMKSAERRIPAPIEDAKASEIKELAIKVFKCLDCSGISRIDFLVEKDTMKIYVNEINTMPGSISFYLWEPTGIKFKDLIDKLIGYAILKNEEHNKNIYVFDTPLLKKASSGVKGGKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FNUK01000003
EMBL· GenBank· DDBJ
SEF52268.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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