A0A1G4SSF4 · A0A1G4SSF4_9HYPH
- ProteintRNA (guanine-N(7)-)-methyltransferase
- GenetrmB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids245 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.
Catalytic activity
- guanosine46 in tRNA + S-adenosyl-L-methionine = N7-methylguanosine46 in tRNA + S-adenosyl-L-homocysteine
Pathway
tRNA modification; N7-methylguanine-tRNA biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 76 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 101 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 128 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 150 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 154 | substrate | ||||
Sequence: K | ||||||
Binding site | 186 | substrate | ||||
Sequence: D | ||||||
Binding site | 224-227 | substrate | ||||
Sequence: TRYE |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | tRNA methyltransferase complex | |
Molecular Function | tRNA (guanine(46)-N7)-methyltransferase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(7)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Xanthobacteraceae > Ancylobacter
Accessions
- Primary accessionA0A1G4SSF4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-23 | Disordered | ||||
Sequence: MTADDESRPFTPVDRPADGAPRE |
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length245
- Mass (Da)27,679
- Last updated2017-11-22 v1
- ChecksumADCA33F35F55EE92
Keywords
- Technical term