A0A1G0E552 · A0A1G0E552_9GAMM

Function

function

This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site70-72substrate
Binding site83substrate
Binding site87-89substrate

GO annotations

AspectTerm
Molecular FunctiondUTP diphosphatase activity
Molecular Functionmagnesium ion binding
Biological ProcessdUMP biosynthetic process
Biological ProcessdUTP catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Deoxyuridine 5'-triphosphate nucleotidohydrolase
  • EC number
  • Short names
    dUTPase
  • Alternative names
    • dUTP pyrophosphatase

Gene names

    • Name
      dut
    • ORF names
      A2V89_01345

Organism names

Accessions

  • Primary accession
    A0A1G0E552

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain18-149dUTPase-like

Sequence similarities

Belongs to the dUTPase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    151
  • Mass (Da)
    16,200
  • Last updated
    2017-01-18 v1
  • Checksum
    3856947589754095
MINIQLKILDKRIGTVYPLPHYATDGSAGLDLRACIDNDLVLKPGGVELIPSGIAIYMADHGYTAMILPRSGMGHKHGIVLGNLVGLIDSDYQGQIMISCWNRGSETFTIVPGERIAQLIIVPVLHANFDVVSDFVTSGRGDGGFGHTGRN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MGXJ01000046
EMBL· GenBank· DDBJ
OGT08310.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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