A0A1F5DHG1 · A0A1F5DHG1_9ARCH
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids682 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H2O + H+(in) = 2 phosphate + 2 H+(out)
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 457 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageArchaea > Candidatus Bathyarchaeota
Accessions
- Primary accessionA0A1F5DHG1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-26 | Helical | ||||
Sequence: YIAPAMALISIITGFYIHGFV | ||||||
Transmembrane | 58-78 | Helical | ||||
Sequence: LGMFVAVMAVVLLLFLPHPIW | ||||||
Transmembrane | 90-111 | Helical | ||||
Sequence: AFAYVFGSVCSAIAGWLGMDVA | ||||||
Transmembrane | 132-158 | Helical | ||||
Sequence: IAFRGGAVMGTSVIGLALAGVSILYFL | ||||||
Transmembrane | 164-186 | Helical | ||||
Sequence: VILGFSFGASAMALFAKAGGGIF | ||||||
Transmembrane | 237-256 | Helical | ||||
Sequence: YVASLMAVMVLGQVLGGYLL | ||||||
Transmembrane | 262-280 | Helical | ||||
Sequence: FAGLGALSSLIGIFAVRVG | ||||||
Transmembrane | 292-312 | Helical | ||||
Sequence: GTYITVVLFMALSYAACTVLG | ||||||
Transmembrane | 318-338 | Helical | ||||
Sequence: WGAATVGLIAGVVIGVTSDYF | ||||||
Transmembrane | 359-385 | Helical | ||||
Sequence: ITIITGFSYGLLSVFPPLVGIGLAAWI | ||||||
Transmembrane | 397-418 | Helical | ||||
Sequence: YGVYGIGVAAFGMLSIVGIVVA | ||||||
Transmembrane | 462-479 | Helical | ||||
Sequence: GFAIGAAGLTVISILAAF | ||||||
Transmembrane | 499-520 | Helical | ||||
Sequence: LVMLGALIGIAIPAVFSSQLML | ||||||
Transmembrane | 595-617 | Helical | ||||
Sequence: YLAGCIFSGLVFALLMSNAGGLW | ||||||
Transmembrane | 661-681 | Helical | ||||
Sequence: LITVIGLVAHMFLPLFLLFSI |
Keywords
- Cellular component
Interaction
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length682
- Mass (Da)70,359
- Last updated2017-01-18 v1
- ChecksumA8CE578734CCAA51