A0A1F5DHG1 · A0A1F5DHG1_9ARCH

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site457Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      A3K81_04335

Organism names

Accessions

  • Primary accession
    A0A1F5DHG1

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane58-78Helical
Transmembrane90-111Helical
Transmembrane132-158Helical
Transmembrane164-186Helical
Transmembrane237-256Helical
Transmembrane262-280Helical
Transmembrane292-312Helical
Transmembrane318-338Helical
Transmembrane359-385Helical
Transmembrane397-418Helical
Transmembrane462-479Helical
Transmembrane499-520Helical
Transmembrane595-617Helical
Transmembrane661-681Helical

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    682
  • Mass (Da)
    70,359
  • Last updated
    2017-01-18 v1
  • Checksum
    A8CE578734CCAA51
MVDAWYIAPAMALISIITGFYIHGFVKKQDPGTARMQFVAGAIKEGARAFLNRMYRTLGMFVAVMAVVLLLFLPHPIWATSNIMGNVTLAFAYVFGSVCSAIAGWLGMDVATDANLRSASAARDGITKAFTIAFRGGAVMGTSVIGLALAGVSILYFLTGDPNVILGFSFGASAMALFAKAGGGIFTKTADIGADLVGKVEMDLPEDDPRNPAVIADNVGDNVGDVAGMGADLYDSYVASLMAVMVLGQVLGGYLLDMPLVFAGLGALSSLIGIFAVRVGEGGDPGSVLNRGTYITVVLFMALSYAACTVLGYDVRFWGAATVGLIAGVVIGVTSDYFTSINRPPTRITAESSVTGPAITIITGFSYGLLSVFPPLVGIGLAAWIAYSVTETIGPGYGVYGIGVAAFGMLSIVGIVVASDSFGPIGDNAKGIAEQGGLDEKTIEILDSLDAAGNTSKAITKGFAIGAAGLTVISILAAFKEVAEAELGAAVAFDLMNPLVMLGALIGIAIPAVFSSQLMLGVGRNAFRMIEEVRRQFREIPGLREGKEGVVPDYAKCVDIATVGALKELLPASVSAIAVTLGVGFIFGVEALGGYLAGCIFSGLVFALLMSNAGGLWDNAKKYIEEGHLGGKGSDAHHAAVIGDTVGDPFKDTAGPSLNTLITVIGLVAHMFLPLFLLFSIF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MEZG01000032
EMBL· GenBank· DDBJ
OGD54609.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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