A0A1D1VIH3 · A0A1D1VIH3_RAMVA

Function

function

Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Protein modification; protein lipoylation via endogenous pathway; protein N6-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.

Features

Showing features for binding site, site, active site.

TypeIDPosition(s)Description
Binding site92-99substrate
Site156Lowers pKa of active site Cys
Binding site159-161substrate
Binding site172-174substrate
Active site190Acyl-thioester intermediate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionlipoyl(octanoyl) transferase activity
Biological Processprotein lipoylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
  • EC number

Gene names

    • Name
      RvY_10829
    • Synonyms
      RvY_10829.1
    • ORF names
      RvY_10829-1

Organism names

Accessions

  • Primary accession
    A0A1D1VIH3

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain48-229BPL/LPL catalytic

Sequence similarities

Belongs to the LipB family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    251
  • Mass (Da)
    28,206
  • Last updated
    2016-11-30 v1
  • Checksum
    B690C8E4291324D8
MSTPARRKILQYCNLGRLRYDKALEIQEQQVQTQLQALDSRKSDGDSHPSPDVLFLVEHEPVYTAGLRKNEFTEVDEGFLRTKGADFHRTNRGGLITFHGPGQLVAYPILNLQRYKPSVRWYVCQLEEVLIKTCQELGVESSRTENTGIWVEGSRKVAAIGLNCRKYITSHGVALNCDTDLTWFGHIVPCGLQGLGVTSLTKERGKHTPINSVVPVFLDKFAEVFNVELEELPFNEPGALNDKVAMKAIIH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BDGG01000005
EMBL· GenBank· DDBJ
GAU99892.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp