A0A1B5D3X1 · A0A1B5D3X1_9PSED

  • Protein
    Glutamyl-Q tRNA(Asp) synthetase
  • Gene
    gluQ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

129520406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site9-13L-glutamate (UniProtKB | ChEBI)
Binding site45L-glutamate (UniProtKB | ChEBI)
Binding site101Zn2+ (UniProtKB | ChEBI)
Binding site103Zn2+ (UniProtKB | ChEBI)
Binding site115Zn2+ (UniProtKB | ChEBI)
Binding site119Zn2+ (UniProtKB | ChEBI)
Binding site172L-glutamate (UniProtKB | ChEBI)
Binding site190L-glutamate (UniProtKB | ChEBI)
Binding site231ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglutamate-tRNA ligase activity
Molecular Functionzinc ion binding
Biological Processglutamyl-tRNA aminoacylation
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamyl-Q tRNA(Asp) synthetase
  • EC number
  • Short names
    Glu-Q-RSs

Gene names

    • Name
      gluQ

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 44 R 15
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A1B5D3X1

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain9-231Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Motif12-22'HIGH' region
Motif228-232'KMSKS' region

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    295
  • Mass (Da)
    33,261
  • Last updated
    2016-11-02 v1
  • Checksum
    40581F6341326E58
MTASTYIGRFAPTPSGHLHFGSLVAALASYLDARANQGRWLMRMEDLDPPREEPGAQAAILHALERYGFEWDGELLRQSERHEAYAKVLNDLFNHGLAYACTCSRKQLEPYNGIYPGLCRNAGHDQQDAAIRLRVPELEYHFTDRVQGPFRQHLGRDAGDFIIRRRDGLYAYQLAVVLDDAWQGVTDIVRGADLLDSTPRQLYLQELLGLRQPRYLHVPLIVQPDGNKLGKSYRSPPLTADQAAPLLLRALRALGQPAGDELLYASPRELLDWGIQQWDATLIPRTLTLAEAQLR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CVTU01000042
EMBL· GenBank· DDBJ
CRM20636.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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