A0A171A7A4 · A0A171A7A4_9BACT
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids712 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Paludibacteraceae > Paludibacter
Accessions
- Primary accessionA0A171A7A4
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 15-25 | 'HIGH' region | ||||
Sequence: PYANGPVHIGH | ||||||
Motif | 338-342 | 'KMSKS' region | ||||
Sequence: KISTS | ||||||
Domain | 610-712 | TRNA-binding | ||||
Sequence: DFMKMDIRVGTVLDCQKVPKADKLLQFRIADGLEERTILSGIAKYYPNPEELIGTQVCFIANFEPRKLRGIMSEGMILSAEDADGKLVLIQPRMTVTNGVEVK |
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length712
- Mass (Da)81,780
- Last updated2016-07-06 v1
- Checksum2EFD05BCBAFE2646
Keywords
- Technical term