A0A161LFU1 · A0A161LFU1_9BACT
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids246 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10-17 | ATP (UniProtKB | ChEBI) | ||||
Sequence: DHGNSAVK | ||||||
Binding site | 90 | substrate | ||||
Sequence: Y | ||||||
Binding site | 97-100 | substrate | ||||
Sequence: GKDR | ||||||
Active site | 99 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 120 | K+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 123 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 175 | substrate | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Paludibacteraceae > Paludibacter
Accessions
- Primary accessionA0A161LFU1
Proteomes
Subcellular Location
Interaction
Structure
Sequence
- Sequence statusComplete
- Length246
- Mass (Da)27,331
- Last updated2016-07-06 v1
- ChecksumEEE47163CB0DE289
Keywords
- Technical term