A0A161LFU1 · A0A161LFU1_9BACT

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site10-17ATP (UniProtKB | ChEBI)
Binding site90substrate
Binding site97-100substrate
Active site99Proton acceptor
Binding site120K+ (UniProtKB | ChEBI)
Binding site123ATP (UniProtKB | ChEBI)
Binding site175substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      PJIAN_4630

Organism names

  • Taxonomic identifier
  • Strain
    • NM7
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Paludibacteraceae > Paludibacter

Accessions

  • Primary accession
    A0A161LFU1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    246
  • Mass (Da)
    27,331
  • Last updated
    2016-07-06 v1
  • Checksum
    EEE47163CB0DE289
MQKSMNLIIDHGNSAVKIAIFEQDRLLVVERYPLLTATIVADFMSRFPVKAIILCSVISIDLHTKQYLQNLPVYFTELTHHTPLPIKNEYETPDTLGKDRIAAAVGANWLLPNANLLIIDAGTAITYDLVSSENTFLGGTISPGAQIRFRALHEFTGKLPLAEEKSTDLLIGKNTIDAITVGVMQGIEFEIEGYITLFMQKYPNLSVFLTGRGSIPFVAKLKNPIFVELNLVLIGLNRILTYNVQL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BDCR01000004
EMBL· GenBank· DDBJ
GAT64085.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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