A0A127Z4E8 · A0A127Z4E8_9BASI

  • Protein
    Related to engulfment and cell motility gene 1 protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    1/5

Function

function

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionSH3 domain binding
Biological Processapoptotic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Related to engulfment and cell motility gene 1 protein

Gene names

    • ORF names
      SPSC_05580

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SscI8
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Ustilaginomycotina > Ustilaginomycetes > Ustilaginales > Ustilaginaceae > Sporisorium

Accessions

  • Primary accession
    A0A127Z4E8

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-21Disordered
Compositional bias7-21Polar residues
Domain369-544ELMO
Region629-660Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    818
  • Mass (Da)
    90,697
  • Last updated
    2016-05-11 v1
  • Checksum
    76A98804E292D9A1
MSGAEPGPSRSGLSNVASPTTTQHSYIDTAAPQLASPQIANRINLVTYGQSTIKALIDPSLPVQDVIRQLCANAHLGVQEPPALFALRDDDDDELIDDANMARKIEAGANFKLCSSPTIEAVEMVDKLSSRDDRTLKMATYTLQRLIRESAFTDEFVARGGVKELLNVIRNRSSGNTLAYALTSCQNLMEGFEYGWDIIDAAFVAKVVTLLVTQERINVCRPATAILKKLVVSGPQDSPKTGRVVTDGRHVATTSTPAVYRYGFEFVYNEIQRERLFLQTLVNRIGSSDTTLKLYSLSLINSLLRNVSDDLFESFTSELEKLNASKAVAWLMDSSRGDELASSILEYQSNVIRAAHRRMRTVVTPTDKRHVHALSYIWLQAKISDVVVPNPAAAQTNPSHDDSRLSVGATTRYKWRRIGFASESAAKEFGRTGWLGLSCLESFVRSDPDLYSKIILEQINRPEERRCMLARASIEVTSILADHWNIESGSYTTSTTYLPFLLSFSKVHHLALRFFLRMWNESGAVASDFTRVSALVRSQVNEALGKQEETSSTWLELEDAFLNSEYRTVRDRQMKELEVDEDYNSKASMRNLRGRIYRESYEFVRQQRIQCLLEGAWFCNVATPAANALSNHSKQRRGSSSTVDTAVPATRATGNGASSGTPKPWRFYRLAPNKKFLYYCDSLERFPIRGGLDDLAERIDLSLVTEVSHHSGAGDTGATGAKATGELVISLLQSADASLAEMQALNPSQFSEWTDGLNMLRGEGGVVSTRETADLIQTLTEIGIKVKLLDLTGEQIELPTTVQPPPLPSTTEFFFAEL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias7-21Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LK056689
EMBL· GenBank· DDBJ
CDR88748.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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