A0A0W0VNM1 · A0A0W0VNM1_9GAMM

  • Protein
    Chromosomal replication initiator protein DnaA
  • Gene
    dnaA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

145050100150200250300350400450
TypeIDPosition(s)Description
Binding site155-162ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA replication origin binding
Biological ProcessDNA replication initiation
Biological Processregulation of DNA replication

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Chromosomal replication initiator protein DnaA

Gene names

    • Name
      dnaA
    • ORF names
      Llon_0927

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ATCC 49505
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Legionellales > Legionellaceae > Legionella

Accessions

  • Primary accession
    A0A0W0VNM1

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain147-356AAA+ ATPase
Domain358-427Chromosomal replication initiator DnaA C-terminal

Sequence similarities

Belongs to the DnaA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    450
  • Mass (Da)
    51,127
  • Last updated
    2016-03-16 v1
  • Checksum
    236DAF861DF19E89
MSANIWQRCLEHLQEEYPAQQFNTWLRPLQCEIEESTLVLLAPNRFVIDWVKKHFYERIKELVGQLSSDAIKLVSIEIGSKMIKPIVVDEQSAKSAPSVKPSPKKSADHYKNTYLNKKFVFDSFVVGNSNQLAQSAAEAVAERPGDAYNPLFIYGGVGLGKTHLMHAIGNAILKNNPEAKVLYLHSERFVADMVKALQTNAINEFKRFYRSLNALLIDDIQFFAGKDRSQEEFFHTFNALLEGQQQIILTSDRYPKEIEGVEERLKSRFGWGLTVAVEPPELETRVAILISKAEQANIDLPYEVAFFIAKRIRSNVRELEGALRRVIANAHFTGKPITIEFVNEALRDLLALQDKLVTIENIQKTVAEYYKVKVADILSKRRSRSIARPRQMAMTLAKELTNHSLPEIGDHFGGRDHTTVIHACRKVKELVQEGGDFAEDYKNLLRTLSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LNYK01000014
EMBL· GenBank· DDBJ
KTD21762.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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