A0A0V0G742 · A0A0V0G742_TRIDM
- ProteinProtein adenylyltransferase Fic
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids428 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 3-O-(5'-adenylyl)-L-threonyl-[protein] + H2O = AMP + H+ + L-threonyl-[protein]
Features
Showing features for site, binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 217 | Important for autoinhibition of adenylyltransferase activity | ||||
Sequence: E | ||||||
Binding site | 299-302 | ATP (UniProtKB | ChEBI) | ||||
Sequence: VGDH | ||||||
Active site | 346 | |||||
Sequence: H | ||||||
Binding site | 350-357 | ATP (UniProtKB | ChEBI) | ||||
Sequence: DGNGRTSR | ||||||
Binding site | 382-383 | ATP (UniProtKB | ChEBI) | ||||
Sequence: YY | ||||||
Binding site | 390 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | AMPylase activity | |
Molecular Function | ATP binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein adenylyltransferase Fic
- EC number
- Alternative names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Cimicomorpha > Reduviidae > Triatominae > Triatoma
Accessions
- Primary accessionA0A0V0G742
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-29 | Helical | ||||
Sequence: FLFTLMLNVAVFILLSFI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Glycosylation | 258 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 268-403 | Fido | ||||
Sequence: LTIEDLLELHRRVLGFVDPTEGGYFRRTQVFVGDHIPPPPSNILPLMQKFLKWLNSWDALSLHPIRYAALAHYKLVHIHPFSDGNGRTSRLLMNMIMMWSGYPPVIILKQDRIRYYEAIKMANRGDIRPFVRFIAE |
Sequence similarities
Belongs to the fic family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length428
- Mass (Da)48,436
- Last updated2016-03-16 v1
- ChecksumA098CC8B7A888A5B
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: F | ||||||
Non-terminal residue | 428 | |||||
Sequence: R |