A0A0U1XGW1 · A0A0U1XGW1_ICHUN

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

139350100150200250300350
TypeIDPosition(s)Description
Binding site87Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site101Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site186Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site200Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site205a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    A0A0U1XGW1

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane34-60Helical
Transmembrane119-137Helical
Transmembrane182-204Helical
Transmembrane233-250Helical
Transmembrane292-312Helical
Transmembrane324-344Helical
Transmembrane356-376Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-213Cytochrome b/b6 N-terminal region profile
Domain214-384Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    393
  • Mass (Da)
    44,357
  • Last updated
    2016-03-16 v1
  • Checksum
    9AC8580E896B9B77
MSHQPSIIRKNNPLLSLGNSMLVDLPSPANISAWWNFGSLLSLCLIMQIITGLILAMHYTANTELAFSSVMHICRDVNNGWLMRNLHANGASMFFIYIYAHIGRGIYYGSYLYKETWNIGVILFTLTAATAFVGYVLPWGQMSFWGATVITNLISATPYVGDDIVVWLWGGFSVSNATLTRFFTFHFILPFILAAMTMIHIMFLHQTGSSNPMGINSNLDKIQFHPYFSFKDILGFVMLLSILFMISLMAPNMLGEPDNFIFANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMAILILLIIPLTHTSKQRGMQFRPLAQTMFWILIANLTLLTWLGGEPAEYPFTTMTQIASTVYFLIFILILPTLGYLEDKILSMPNKLKYSLIQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM267717
EMBL· GenBank· DDBJ
AIT96687.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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