A0A0R2ZTL4 · A0A0R2ZTL4_9PSED

  • Protein
    Ribosomal RNA large subunit methyltransferase E
  • Gene
    rlmE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

Catalytic activity

Features

Showing features for binding site, active site.

121620406080100120140160180200
TypeIDPosition(s)Description
Binding site60S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site62S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site80S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site96S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site121S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site161Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionrRNA (uridine-2'-O-)-methyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribosomal RNA large subunit methyltransferase E
  • EC number
  • Alternative names
    • 23S rRNA Um2552 methyltransferase
    • rRNA (uridine-2'-O-)-methyltransferase

Gene names

    • Name
      rlmE
    • Synonyms
      ftsJ
      , rrmJ
    • ORF names
      SAMN04490197_2793

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BS2775
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A0R2ZTL4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain28-204Ribosomal RNA methyltransferase FtsJ

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    216
  • Mass (Da)
    24,111
  • Last updated
    2016-01-20 v1
  • Checksum
    06AF82B2E14271B0
MARSKTSLKWLQEHFNDPYVKKAQKDGYRSRASYKLLEIQDKDKLIRPGMSVIDLGAAPGGWSQVTSRLIGGQGRLIASDILEMDSIPDVTFVHGDFTQDAVLAQILEAVGNSQVDLVISDMAPNMSGLPAVDMPRAMFLCELALDLAGRVLRPGGDFLVKVFQGEGFDEYHKNIRKLFDKVQTRKPDSSRDRSREQYLLCRGFRGVEGAASEERF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LT629782
EMBL· GenBank· DDBJ
SDU09683.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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