A0A0Q9C5E6 · A0A0Q9C5E6_9CELL

Function

function

RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.
    EC:2.7.7.101 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per monomer.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular ComponentDNA-directed RNA polymerase complex
Cellular Componentprimosome complex
Molecular FunctionDNA binding
Molecular FunctionDNA primase activity
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA primase
  • EC number

Gene names

    • Name
      dnaG
    • ORF names
      ASE27_10040

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Root918
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Cellulomonadaceae > Oerskovia

Accessions

  • Primary accession
    A0A0Q9C5E6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer. Interacts with DnaB.

Family & Domains

Features

Showing features for zinc finger, domain, region, compositional bias.

TypeIDPosition(s)Description
Zinc finger41-65CHC2-type
Domain262-359Toprim
Region458-491Disordered
Compositional bias462-489Pro residues

Domain

Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.

Sequence similarities

Belongs to the DnaG primase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    645
  • Mass (Da)
    69,814
  • Last updated
    2016-01-20 v1
  • Checksum
    188C1288D1B6A560
MAGLIRREDVDAVRERARIDEIVSSHVTLKPAGVGSLKGLCPFHDERSPSFHVRPQVGRWHCFGCNEGGDVISFVQKIDGMTFTEAVEYLADRVGIQLRYEEGGGPRRTEEPGKRQRLLEAHRVASQFFSEQLFAPGATVARTFLAERSFDRSDAERFGVGFAPTGWDALLRHLRGRGFTEAELIASGLMSQGQRGIYDRFRGRLVWPIRDVTGETIGFGARKLFDEDQGPKYLNTPETTLYKKSQVLYGIDLAKREIAKNKRVVVVEGYTDVMAAHLSGITTAVATCGTAFGSDHARIVRRLLGDTTAGGGLQLASGASLGGEIVFTFDGDAAGQKAAVRAFGEDQRFYAQTFVAVEPSGMDPCELRMAHGPEGVRALVEGRQPLFEFVIRTTLDTFDLDTAEGRVAALRAAAPVVAGIRDTALRPEYARMLAGWIGMDSESVRRAVAAAGKAGVPQTLPAPVRPLSPTPDDAAPAAPSGPVFSPPDPRDPVARLERQALVVALQYPQFVPAEEFDAFSESAFATPAWRAVHDAIRAAGGMAGSAAHPAGQWVEAVIEQSPETVRGIVNQLAVAPLPEDRENVIQGYVKGVIKAFVDLGLTRRVADAKSRLQRLDPAGDQEAYGAAFAELLAVERERRELREGA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias462-489Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LMJG01000013
EMBL· GenBank· DDBJ
KRD36788.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp