A0A0Q6FG50 · A0A0Q6FG50_9HYPH
- ProteinMethylenetetrahydrofolate reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids299 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H+This reaction proceeds in the backward direction.
Cofactor
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway.
One-carbon metabolism; tetrahydrofolate interconversion.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | FAD binding | |
Molecular Function | methylenetetrahydrofolate reductase (NADH) activity | |
Biological Process | methionine biosynthetic process | |
Biological Process | tetrahydrofolate interconversion |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylenetetrahydrofolate reductase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Aurantimonadaceae > Aurantimonas
Accessions
- Primary accessionA0A0Q6FG50
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)33,043
- Last updated2016-01-20 v1
- ChecksumF18B4798CF3EB036
Keywords
- Technical term