A0A0P0N2X4 · A0A0P0N2X4_9CREN
- ProteinPyridoxal 5'-phosphate synthase subunit PdxT
- GenepdxT
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids200 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
Catalytic activity
- H2O + L-glutamine = L-glutamate + NH4+
Pathway
Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 52-54 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: GES | ||||||
Active site | 84 | Nucleophile | ||||
Sequence: C | ||||||
Binding site | 116 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 145-146 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: IR | ||||||
Active site | 181 | |||||
Sequence: H | ||||||
Active site | 181 | Charge relay system | ||||
Sequence: H | ||||||
Active site | 183 | |||||
Sequence: E | ||||||
Active site | 183 | Charge relay system | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | glutaminase complex | |
Molecular Function | glutaminase activity | |
Molecular Function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity | |
Biological Process | glutamine catabolic process | |
Biological Process | pyridoxal phosphate biosynthetic process | |
Biological Process | pyridoxine metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyridoxal 5'-phosphate synthase subunit PdxT
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Desulfurococcales > Pyrodictiaceae > Pyrodictium
Accessions
- Primary accessionA0A0P0N2X4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length200
- Mass (Da)22,003
- Last updated2016-01-20 v1
- ChecksumFEDF8C475624E417
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP013011 EMBL· GenBank· DDBJ | ALL00456.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NCQP01000007 EMBL· GenBank· DDBJ | OWJ53930.1 EMBL· GenBank· DDBJ | Genomic DNA |