A0A0P0N2X4 · A0A0P0N2X4_9CREN

  • Protein
    Pyridoxal 5'-phosphate synthase subunit PdxT
  • Gene
    pdxT
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site52-54L-glutamine (UniProtKB | ChEBI)
Active site84Nucleophile
Binding site116L-glutamine (UniProtKB | ChEBI)
Binding site145-146L-glutamine (UniProtKB | ChEBI)
Active site181
Active site181Charge relay system
Active site183
Active site183Charge relay system

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentglutaminase complex
Molecular Functionglutaminase activity
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processglutamine catabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxT
  • EC number
  • Alternative names
    • Pdx2
    • Pyridoxal 5'-phosphate synthase glutaminase subunit
      (EC:3.5.1.2
      ) . EC:3.5.1.2 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      pdxT
    • ORF names
      Pdsh_08565
      , Pyrde_0406

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Su06
    • Hulk
  • Taxonomic lineage
    Archaea > Thermoproteota > Thermoprotei > Desulfurococcales > Pyrodictiaceae > Pyrodictium

Accessions

  • Primary accession
    A0A0P0N2X4

Proteomes

Subcellular Location

Interaction

Subunit

In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glutaminase PdxT/SNO family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    22,003
  • Last updated
    2016-01-20 v1
  • Checksum
    FEDF8C475624E417
MKVGIVALQGGFCEHVYMLRKLAEETGWSIEPVLVKKPSNLRGLDAVIIPGGESTTIGVVARRIGLLDELRDLLESGLPAMGTCAGATLLAKSVRDRVVGETRQPLLAVMNIEVVRNYYGRQRESFEVDLKIPVLGEKPFRGVFIRAPAITRLWGRAKGIAELDGVTVAAEEDGKLALAFHPELTGDTRIHRYFIENIKR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP013011
EMBL· GenBank· DDBJ
ALL00456.1
EMBL· GenBank· DDBJ
Genomic DNA
NCQP01000007
EMBL· GenBank· DDBJ
OWJ53930.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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