A0A0L0LJB5 · A0A0L0LJB5_9BACT

Function

function

The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell envelope Sec protein transport complex
Cellular Componentplasma membrane
Molecular Functionprotein transmembrane transporter activity
Molecular Functionsignal sequence binding
Biological Processprotein transport by the Sec complex
Biological ProcessSRP-dependent cotranslational protein targeting to membrane, translocation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein translocase subunit SecY

Gene names

    • Name
      secY
    • ORF names
      AB203_03340

Organism names

Accessions

  • Primary accession
    A0A0L0LJB5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-40Helical
Transmembrane69-96Helical
Transmembrane117-137Helical
Transmembrane149-168Helical
Transmembrane175-197Helical
Transmembrane209-229Helical
Transmembrane263-286Helical
Transmembrane306-326Helical
Transmembrane360-382Helical
Transmembrane388-409Helical

Keywords

Interaction

Subunit

Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the SecY/SEC61-alpha family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    421
  • Mass (Da)
    44,874
  • Last updated
    2015-11-11 v1
  • Checksum
    1EB18D9FEEC2B926
MVANFFNKLRLTFADKALRNRILFVLGAIAVFRFLAAIPIPGVDRVALEQFFLNNQFLGLLNVFSGGGFSYVSIVMLGVGPYITASIIMQLGTVIFPRVKAMYSEEGEAGRTQFISIARMITIPIAILQSVAFLSLLESQHVLLPLSPFSFAINVFLAAAGSLLLMWIGELITEFGIGNGVSLIIFAGIIAGLPSAVSQAIFTASTENIPAYLGFLALAIAVVYSVVLVSEAERSIPIAYARQARGAANAATYLPIRLLQAGVIPIIFALSLLLLPQMLFSALGAMGVAGATGLAAGYTTFVNNPYAYGAAYFVLVIMFTFFYTTITFEPKRVADNLQKSGAFVPGVRPGRETEAYINSVVTRVTLPGAVFLGLVAVIPFIVKGITGISAVLVGGTALLIAVQVLLDLIRKVDAHASLREY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LFCR01000002
EMBL· GenBank· DDBJ
KND49995.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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