A0A0E2LGN3 · A0A0E2LGN3_ECOU3

Function

function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyl-diphosphatase activity
Biological Processcell wall organization
Biological Processdephosphorylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-diphosphatase
  • EC number
  • Alternative names
    • Bacitracin resistance protein
    • Undecaprenyl pyrophosphate phosphatase

Gene names

    • Name
      uppP
    • ORF names
      G925_03296

Organism names

Accessions

  • Primary accession
    A0A0E2LGN3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane50-69Helical
Transmembrane90-110Helical
Transmembrane116-136Helical
Transmembrane195-213Helical
Transmembrane225-246Helical
Transmembrane252-272Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the UppP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    29,773
  • Last updated
    2015-05-27 v1
  • Checksum
    1CFAC099D0463357
MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AWBU01000022
EMBL· GenBank· DDBJ
EQX25987.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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