A0A0D3LG79 · A0A0D3LG79_9BACT
- Protein3'-phosphate/5'-hydroxy nucleic acid ligase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids471 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 145 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 222-226 | GMP (UniProtKB | ChEBI) | ||||
Sequence: NHFVE | ||||||
Binding site | 223 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 252 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 334 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 334-335 | GMP (UniProtKB | ChEBI) | ||||
Sequence: HN | ||||||
Binding site | 367-370 | GMP (UniProtKB | ChEBI) | ||||
Sequence: PGSM | ||||||
Active site | 391 | GMP-histidine intermediate | ||||
Sequence: H | ||||||
Binding site | 391-394 | GMP (UniProtKB | ChEBI) | ||||
Sequence: HGAG |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA ligase activity | |
Molecular Function | GTP binding | |
Molecular Function | manganese ion binding | |
Molecular Function | RNA ligase (GTP) activity | |
Biological Process | DNA repair | |
Biological Process | RNA processing | |
Biological Process | RNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3'-phosphate/5'-hydroxy nucleic acid ligase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Cytophagia > Cytophagales > Flammeovirgaceae
Accessions
- Primary accessionA0A0D3LG79
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length471
- Mass (Da)51,285
- Last updated2015-05-27 v1
- Checksum332B0A664A99491E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP004371 EMBL· GenBank· DDBJ | AHM60908.1 EMBL· GenBank· DDBJ | Genomic DNA |