A0A0C4WRU9 · A0A0C4WRU9_9GAMM

Function

function

Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

131950100150200250300
TypeIDPosition(s)Description
Binding site88carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site102carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site107carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site126carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site176-177carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site192carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site196carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site311carboxy-S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionmethyltransferase activity
Molecular Functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Processmethylation
Biological ProcesstRNA wobble uridine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA U34 carboxymethyltransferase
  • EC number

Gene names

    • Name
      cmoB
    • ORF names
      Achr_28900

Organism names

Accessions

  • Primary accession
    A0A0C4WRU9

Proteomes

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    319
  • Mass (Da)
    36,026
  • Last updated
    2015-04-29 v1
  • Checksum
    9A40414971F8FBB3
MIDLSPLVRRLAGTPLAAWADSLPAQLDDRLTRSHGDLQRWQAALQALPMLTAEHIELGEQLQLAGACDDTNRAALRQALLGLSPWRKGPFDLFGVHVDTEWRSDWKWQRVAPHLELRGRRILDVGCGNGYYMWRMLGAGADCVVGIDPNWLFFCQFLALRRYLPELPAWHLPLALEDLPEKLEGFDTVFSMGVLYHRRSPIDHLLALKDCLRRGGELLLETLVVDGDASTVLVPEDRYAQMRNVWFLPSVAALELWLRRAGFVEVCCVDVAVTSVEEQRATEWMTFQSLPDFLDPTDHGRTVEGLPAPTRATLLARKP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP010415
EMBL· GenBank· DDBJ
AJE22305.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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