A0A0B4EJ61 · A0A0B4EJ61_9RHOB
- ProteinThymidine phosphorylase
- GenedeoA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids433 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
Catalytic activity
- thymidine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + thymine
Pathway
Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 1,4-alpha-oligoglucan phosphorylase activity | |
Molecular Function | thymidine phosphorylase activity | |
Biological Process | pyrimidine nucleobase metabolic process | |
Biological Process | thymidine metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThymidine phosphorylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Roseobacteraceae > Leisingera
Accessions
- Primary accessionA0A0B4EJ61
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 345-419 | Pyrimidine nucleoside phosphorylase C-terminal | ||||
Sequence: HIAAMNGEALGLAVVALGGGRMVESDRIHPGVGISDIVRLGQPVGAGDRLARIHAASDDAAEMAEAAFLAAIAIG |
Sequence similarities
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length433
- Mass (Da)44,004
- Last updated2015-03-04 v1
- Checksum90BBA99353EF292F
Keywords
- Technical term