A0A097QHD8 · A0A097QHD8_9ROSA
- ProteinIsocitrate lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids575 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Involved in storage lipid mobilization during the growth of higher plant seedling.
Catalytic activity
- D-threo-isocitrate = glyoxylate + succinate
Cofactor
Note: Can also use Mn2+ ion.
Pathway
Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 104-106 | substrate | ||||
Sequence: SGW | ||||||
Binding site | 175 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Active site | 213 | Proton acceptor | ||||
Sequence: C | ||||||
Binding site | 214-215 | substrate | ||||
Sequence: GH | ||||||
Binding site | 250 | substrate | ||||
Sequence: R | ||||||
Binding site | 437-441 | substrate | ||||
Sequence: NLSPS | ||||||
Binding site | 472 | substrate | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | glyoxysome | |
Molecular Function | isocitrate lyase activity | |
Molecular Function | metal ion binding | |
Biological Process | glyoxylate cycle | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsocitrate lyase
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Rosales > Rosaceae > Amygdaloideae > Amygdaleae > Prunus
Accessions
- Primary accessionA0A097QHD8
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length575
- Mass (Da)64,368
- Last updated2015-01-07 v1
- Checksum5E0A9D1B5992BE65