A0A097KPK6 · A0A097KPK6_9VIRI

  • Protein
    DNA-directed RNA polymerase subunit alpha
  • Gene
    rpoA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentchloroplast
Cellular ComponentDNA-directed RNA polymerase complex
Cellular Componentmembrane
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionprotein dimerization activity
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit alpha
  • EC number
  • Short names
    PEP
  • Alternative names
    • Plastid-encoded RNA polymerase subunit alpha
      (RNA polymerase subunit alpha
      )

Gene names

    • Name
      rpoA

Encoded on

  • Chloroplast

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Klebsormidiophyceae > Klebsormidiales > Klebsormidiaceae > Interfilum

Accessions

  • Primary accession
    A0A097KPK6

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane364-384Helical

Keywords

Interaction

Subunit

In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-263Alpha N-terminal domain (alpha-NTD)
Domain20-243DNA-directed RNA polymerase RpoA/D/Rpb3-type
Region279-412Alpha C-terminal domain (alpha-CTD)

Domain

The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

Sequence similarities

Belongs to the RNA polymerase alpha chain family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    412
  • Mass (Da)
    47,400
  • Last updated
    2015-01-07 v1
  • Checksum
    592E51A291A231A4
MENFLLTCIESRVENNTSFYGRFQLGPFEGGQGLTIANAFRRVLLSELSGLAIVGVEIQGVTHEYSYLKGIRESILDILLNLKKIVLTSDFDCKEKQIAYLNVQGPAKIKAKDLKLPLSLQCVDPEQYIATLSHDGNLVMKLLICHGKNYSIQNNEYKNLTKKISFFEKNKIEKNLFKNLLPIDSIYMPIKKVNYIVESDDDTIELKDRIILEIWTNGSIHPRQAIHNAAKILVQLFFPFQETQPLKSLFLNTKNIKVLNYLENNTSVNFFTKKHNSLIDKKLGSLDIGNLDLSLRPYTCLKRANIHTIGDLLKYSKEELLLLKNFGKRSLEEVETNLFQIGLKLKNTNGIDITLIKNKLKKQIYNLLCIFIFYFFQFFFYYLLVENISKKKKNVFTAAQRMKSSVASPAKQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM462881
EMBL· GenBank· DDBJ
AIT95124.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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