A0A075WP33 · A0A075WP33_ARCFL

Function

function

Component of a hydro-lyase that catalyzes the dehydration of mevalonate 5-phosphate (MVA5P) to form trans-anhydromevalonate 5-phosphate (tAHMP). Involved in the archaeal mevalonate (MVA) pathway, which provides fundamental precursors for isoprenoid biosynthesis, such as isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway.

Keywords

  • Molecular function
  • Ligand
    • #Iron

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomevalonate dehydratase large subunit
  • EC number

Gene names

    • ORF names
      AFULGI_00026330

Organism names

Accessions

  • Primary accession
    A0A075WP33

Proteomes

Interaction

Subunit

Heterodimer composed of a large subunit (PMDh-L) and a small subunit (PMDh-S).

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-368Phosphomevalonate dehydratase large subunit-like

Sequence similarities

Belongs to the AcnX type II large subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    372
  • Mass (Da)
    41,850
  • Last updated
    2014-10-29 v1
  • Checksum
    AF2200680707A32A
MYLTKDEERLLESDNDTIRKCMEILVAEGEANEAERLVEVKSAHISGVSYDNIGEAGLEWLESLDAKLKVPATLNPAGMDVERWREMGIDEEFHEKQMRVLRVFERLGVRMTLTCTPYYLLRPEFGDHLAWAESSAIVYANSIIGARTERESGPSAIAAAIIGKIPYYGVHIKENRAPTIFVRLKGDLAAAGYKAGRELRDQIPYFVFDRSVTEEELKLLGAALAATGNTVMFHAENYTPEWKDFEKPAEKIEVDDRLERACEPDLITIGCPHASVRELETILKLMGGRKAKKEFWVFTARDVARKAEKIVQKLEELGVKVFSDTCMVVSPATSKFRCIMVNSGKALYYLPNKRDVDVAFGDLRKCVETAVS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP006577
EMBL· GenBank· DDBJ
AIG99343.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp