A0A067XPJ1 · A0A067XPJ1_ZOAVI
- ProteinRhodopsin
- GeneRhod
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids245 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling.
Features
Showing features for site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | photoreceptor outer segment | |
Molecular Function | G protein-coupled photoreceptor activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to light stimulus | |
Biological Process | phototransduction | |
Biological Process | visual perception |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRhodopsin
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Cottioidei > Zoarcales > Zoarcidae > Zoarcinae > Zoarces
Accessions
- Primary accessionA0A067XPJ1
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 31-51 | Helical | ||||
Sequence: ILLNLAVADLFMVLGGFTTTM | ||||||
Transmembrane | 71-89 | Helical | ||||
Sequence: FFATLGGEIALWSLVVLAI | ||||||
Transmembrane | 110-129 | Helical | ||||
Sequence: IMGLAFTWVMASACAVPPLV | ||||||
Transmembrane | 159-179 | Helical | ||||
Sequence: FVIYMFTCHFVIPMVVIFFCY | ||||||
Transmembrane | 210-232 | Helical | ||||
Sequence: VVIMVIAYLVCWVPYASVAWWIF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 66↔143 | |||||
Sequence: CNVEGFFATLGGEIALWSLVVLAIERWVVVCKPISNFRFSEDHAIMGLAFTWVMASACAVPPLVGWSRYIPEGMQCSC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-224 | G-protein coupled receptors family 1 profile | ||||
Sequence: VNFLTLYVTLEHKKLRTPLNYILLNLAVADLFMVLGGFTTTMYTSMHGYFVLGRLGCNVEGFFATLGGEIALWSLVVLAIERWVVVCKPISNFRFSEDHAIMGLAFTWVMASACAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFTCHFVIPMVVIFFCYGRLLCAVKEAAAAQQESETTQRAEKEVSRMVVIMVIAYLVCWVPY |
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Keywords
- Domain
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusFragment
- Length245
- Mass (Da)27,624
- Last updated2014-10-01 v1
- Checksum9D70B890AC2CB554
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: F | ||||||
Non-terminal residue | 245 | |||||
Sequence: T |