A0A022WB80 · A0A022WB80_TRIRU

Function

function

Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentnuclear membrane
Cellular Componentperinuclear region of cytoplasm
Molecular Functionubiquitin binding
Molecular Functionubiquitin protein ligase binding
Biological ProcessmRNA transport
Biological Processprotein transport
Biological Processubiquitin-dependent protein catabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Nuclear protein localization protein 4

Gene names

    • ORF names
      H103_02041

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 288.86
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Arthrodermataceae > Trichophyton

Accessions

  • Primary accession
    A0A022WB80

Proteomes

Subcellular Location

Cytoplasm, perinuclear region
Endoplasmic reticulum membrane
; Peripheral membrane protein
Nucleus membrane
; Peripheral membrane protein

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region40-62Disordered
Compositional bias42-62Polar residues
Compositional bias93-107Polar residues
Region93-141Disordered
Compositional bias108-128Basic and acidic residues
Domain270-407MPN
Region608-652Disordered
Compositional bias619-641Polar residues

Sequence similarities

Belongs to the NPL4 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    652
  • Mass (Da)
    72,591
  • Last updated
    2014-06-11 v1
  • Checksum
    9575811423924BF8
MASPRPIILRFESRNGQFRLTVSPTEQFTALLPKILENLPKDTDPTTVSLSNKPIGTGGQERNLTTLKGISIQRVGLSHGDKLFVGYEEQKSTANGSLNGQTGATKKQESSHRLDGGAVPERDDSSSTKRPTSPTAIIKNPWEIVRQSDLDNRLDKKDGKIPRSLDQKMCRHGPKGMCDYCMPLEPYAPEYLAEKKIKHLSFNSYLRKINSSTNKPELKSSYMPPLSEPFYRVRKDCPSGHPAWPEGICTKCQPSAITLQPQQFRMVDHVEFSSPDLINSLLDFWRKTGSQRIGFLYGTYEEYTEVPLGIKAVVQAIYEPPQVDEVDGVTLHEWNNEKDVDHVAKLCGMEKIGVIFTDLIDAGAGDGTVVCKRHIDSYYLSSLEVVFASQLQARNPKPCKWSETGQFGSNFVTCVLSGDENGAISVCAYQASNSAVEMVRADIIEPSADPSVMLVQQEDELNNANITRYIPEVFYRRINEYKVSVQENAKPSFPVEYLFVTLTHGFPTTPTTVFTDTSFPIENREFIGESQDLRRVASKLTDSSDPNTIIKAVSNFHLLTFLHGMGILNEDEEALLCTVATKHDPADGIQLLNTAGWATLVTILQESGETPPKRSWPFKRQSPISSSFHNSSHNSNSDGEQLAKRFRGASLE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias42-62Polar residues
Compositional bias93-107Polar residues
Compositional bias108-128Basic and acidic residues
Compositional bias619-641Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KK207751
EMBL· GenBank· DDBJ
EZF55411.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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