Q26304 · LUCI_LUCMI
- ProteinLuciferin 4-monooxygenase
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids548 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Produces green light with a wavelength of 570 nm.
Catalytic activity
- ATP + firefly D-luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu
Cofactor
Activity regulation
Inhibited by ATP analogs and sodium deoxycholate. Activated by choline-containing phospholipids.
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
11.5 μM | luciferin | |||||
130 μM | ATP |
pH Dependence
Optimum pH is 7.7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity | |
Biological Process | bioluminescence |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLuciferin 4-monooxygenase
- EC number
- Short namesLuciferase
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Elateriformia > Elateroidea > Lampyridae > Luciolinae > Luciola
Accessions
- Primary accessionQ26304
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000193145 | 1-548 | Luciferin 4-monooxygenase | |||
Sequence: MEMEKEENVVYGPLPFYPIEEGSAGIQLHKYMHQYAKLGAIAFSNALTGVDISYQEYFDITCRLAEAMKNFGMKPEEHIALCSENCEEFFIPVLAGLYIGVAVAPTNEIYTLRELNHSLGIAQPTIVFSSRKGLPKVLEVQKTVTCIKKIVILDSKVNFGGHDCMETFIKKHVELGFQPSSFVPIDVKNRKQHVALLMNSSGSTGLPKGVRITHEGAVTRFSHAKDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYFACGYRVVMLTKFDEELFLRTLQDYKCTSVILVPTLFAILNKSELIDKFDLSNLTEIASGGAPLAKEVGEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDKPGASGKVVPLFKVKVIDLDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWLHTGDIGYYDEDEHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPDAGELPGAVVVMEKGKTMTEKEIVDYVNSQVVNHKRLRGGVRFVDEVPKGLTGKIDAKVIREILKKPQAKM |
Interaction
Structure
Sequence
- Sequence statusComplete
- Length548
- Mass (Da)60,495
- Last updated1996-11-01 v1
- Checksum62C8953BDFFBC423
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
S61961 EMBL· GenBank· DDBJ | AAB26932.1 EMBL· GenBank· DDBJ | mRNA |